Senna Research

1. Sennosides stimulate colon activity and increase fluid secretion by the colon, with the effect of softening the stool and increasing its bulk. Double-blind trials have confirmed the benefit of senna in treating constipation, constipation induced by drugs, as a preparatory agent for bowel surgery. Surgeons rated the efficacy of senna at clearing the bowels at 70%, compared to 58% efficacy for PEG. For more informations :
   
   http://www.vitacost.com/science/hn/Herb/Senna.htm
   
   http://www.truestarhealth.com/Notes/2165007.html
   
   
   

2. Cassia angustifolia was found to contain gum which was comparable to others utilised in pharmaceutical industry. Hence, effects of gamma radiations, ethyl methane sulfonate and sodium azide on the gum content in Senna were investigated. It was found that ethyl methane sulfonate enhanced the gum content. Utilisation of the plants with higher gum content can make Cassia angustifolia a feasible dual source of gum and sennosides.
   
   Ref : http://www.actahort.org/books/253/253_14.htm
   
   
   

3. Extensive research during the last 50 years has led to a clear understanding of senna's action. The sennosides irritate the lining of the large intestine, causing the muscles to contract strongly, resulting in a bowel movement about 10 hours after the dose is taken. They also stop fluid from being absorbed from the large bowel, helping to keep the stool soft. More information on how to use the senna in different forms as a remedy for constipation;
   
   Ref : http://www.herbs2000.com/herbs/herbs_senna.htm